In 1981, when AIDS was first called GRID (Gay Related Immune Disorder), and the HIV virus had not yet been discovered, important research on the immune modulating effects of dimethylglycine was published in the Journal of Infectious Diseases (1).
Graber CD et al state that dimethylglycine presumably “enhances oxygen utilization by tissue and complexes free radicals.” In a double-blind study on 20 humans, they found a fourfold increase in antibody response to vaccines as compared to controls. In studying cell-mediated immune responses to phytohemagglutinin, convanavalin A and pokeweed mitogen, they found an almost threefold increase in responses. They concluded that DMG enhanced both arms of the immune system.
Sublingual DMG is probably a more effective methyl donor that oral TMG or oral DMG. Increased oxygen utilization inside the cells can inactivate intracellular viruses, fungus and bacteria. Folic acid supports an enzyme that breaks down DMG and the breakdown products are likely where the benefits reside. Liquid B12 and Folic acid by Bricker Labs also taken under the tongue would be a good choice to use along with DMG. Folic acid supports the methylation process.
1. Immunomodulating properties of dimethylglycine in humans, Graber CD et al; J. Infect Dis 1981 Jan;143(1):101-5.
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